Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife® Perfexion™

نویسندگان

  • Tuan-Anh Tran
  • Vincent Wu
  • Harish Malhotra
  • James P. Steinman
  • Dheerendra Prasad
  • Matthew B. Podgorsak
چکیده

BACKGROUND The GammaPlan(™) treatment planning system (TPS) does not fully account for shutter dose when multiple shots are required to deliver a patient's treatment. The unaccounted exposures to the target site and its periphery are measured in this study. The collected data are compared to a similar effect from the Gamma Knife(®) model 4C. MATERIALS AND METHODS.: A stereotactic head frame was attached to a Leksell(®) 16 cm diameter spherical phantom; using a fiducial-box, CT images of the phantom were acquired and registered in the TPS. Measurements give the relationship of measured dose to the number of repositions with the patient positioning system (PPS) and to the collimator size. An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site and all measurements were acquired with an ionization chamber. RESULTS Measured dose increases with frequency of repositioning and with collimator size. As the radiation sectors transition between the beam on and beam off states, the target receives more shutter dose than the periphery. Shutter doses of 3.53±0.04 and 1.59±0.04 cGy/reposition to the target site are observed for the 16 and 8 mm collimators, respectively. The target periphery receives additional dose that varies depending on its position relative to the target. CONCLUSIONS The radiation sector motions for the Gamma Knife(®) Perfexion(™) result in an additional dose due to the shutter effect. The magnitude of this exposure is comparable to that measured for the model 4C.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of Organ Specific peripheral dose for Gamma knife 4C based on Monte Carlo

Introduction: Stereotactic Gamma Knife radiosurgery has been widely used for treating brain tumors. The scattered radiation outside of treatment field (peripheral dose) can induce the secondary cancer to specific organ. This paper investigated the absorbed dose to eyes, thyroid, heart, lung, breast and colon using a Monte Carlo technique for Mird phantom. We also study the ef...

متن کامل

Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device

The GammaPlan treatment planning system does not account for the leakage and scatter dose during APS repositioning. In this study, the dose delivered to the target site and its periphery from the defocus stage and intershot couch transit (couch motion from the focus to defocus position and back) associated with APS repositioning are measured for the Gamma Knife model 4C. A stereotactic head-fra...

متن کامل

Assessment of basic physical and dosimetric parameters of synthetic single-crystal diamond detector and its use in Leksell Gamma Knife and CyberKnife small radiosurgical fields

Background: To determine the basic physical and dosimetric properties of a new synthetic single-crystal diamond detector and its application for relative small field dosimetry. Materials and Methods: The pre-irradiation dose required to stabilize detector response, dose rate dependence, photon and electron energy dependence, temperature dependence and angular dependence of MicroDiamond detector...

متن کامل

Evaluation of the Effects of Inhomogeneities on Dose Profiles Using Polymer Gel Dosimeter and Monte Carlo Simulation in Gamma Knife

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

متن کامل

Two‐year experience with the commercial Gamma Knife Check software

The Gamma Knife Check software is an FDA approved second check system for dose calculations in Gamma Knife radiosurgery. The purpose of this study was to evaluate the accuracy and the stability of the commercial software package as a tool for independent dose verification. The Gamma Knife Check software version 8.4 was commissioned for a Leksell Gamma Knife Perfexion and a 4C unit at the Univer...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 45  شماره 

صفحات  -

تاریخ انتشار 2011